Assessment of Vitamin B12 Status in Patients with Morbid Obesity

Vitamin B12 (VB12) is an essential water-soluble vitamin that also known as Cobalamin [1]. It is composed of a corrin ring consisting of four pyrrole units and a cobalt ion at the center of the ring [2]. 1VB12 is manufactured by microorganisms present in the liver of animals bound to protein. The average B12 content of liver tissue is approximately 1.0 microgram/g of tissue in healthy adults [3]. The various forms of cobalamin include cyanocobalamin, hydroxycobalamin, methyl cobalamin and 5-deoxyadenosylcobalamin, with the active forms of B12 in human metabolism being methyl cobalamin and 5-deoxyadenosylcobalamin [1].